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21c Museum Hotel Lexington

Lexington, United States, North America

21c Museum Hotel Lexington is an 88-room boutique hotel, contemporary art museum, cultural center and home to Lockbox restaurant, led by executive chef Jonathan Searle. 


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Four star


What can you expect to see when you visit 21c? Nothing expected, that’s for sure. Check out the highlights from the current exhibitions at 21c Lexington and then come see them for yourself. With more than 7,000 square feet of exhibition space, curiosity will lead you to discover something new around every corner. Our galleries are open daily and feature rotating exhibitions, so visit often and make sure to take advantage of regular cultural programming.

With high ceilings and large historic windows, guests rooms feel residential and serve as, a comfortable respite from the thought-provoking art and activity that fills the museum galleries. Outfitted with custom-designed contemporary furnishings, comfortable beds, plush robes, and Malin + Goetz bath amenities, the spaces are designed to leave you feeling refreshed and restored.


  • 88 rooms
  • 5 suites
  • 15 floors




  • High Speed Internet
  • Bar
  • Restaurant


Lockbox is committed to sourcing local, high-quality ingredients around the Bluegrass region. Led by executive chef Jonathan Searle, Lockbox uses thoughtful yet simple preparations and cooking techniques in a contemporary setting. Designed by Deborah Berke Partners, the Lockbox space highlights historic features like original marble floors, decorative plaster details and large windows. Communal tables in both the dining room and lounge provide opportunities for large groups to dine together, or for individual guests to meet new people while they dine.


Out and About Gay Travel Guides are available at each and every World Rainbow Hotel. They are prepared by the concierge and staff at the hotel and aim to provide you with up to date information about the local gay and lesbian scene.

Find out more about Out and About Gay Travel Guides here.

You can add your comments and suggestions about the local gay scene at this hotel.


About the Location

Positioned smack dab at the intersection of quaint southern charm and big city tastes, Lexington is the jewel in the crown of the Bluegrass region. Horses reign king, of course, but there is so much more to our flourishing community. Are you a beer enthusiast? A culture addict? A basketball fanatic? Use our area guide to explore the rich culture of the city fondly nicknamed the Athens of the West.

Street Address

167 West Main Street,
Lexington, Kentucky, United States,
40507, North America


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